Pizza
Wise Guys Pizzeria - Roanoke
Orders through Toast are commission free and go directly to this restaurant
Food/Pizza's
Starters
10 Pieces Italian Hot Wings
Wise Guys hot sauce is a perfect mix of Dijon mustard, grated horseradish, garlic butter & Frank's hot sauce. BBQ sauce also available$15.95
6 Pieces Italian Hot Wings
Wise Guys hot sauce is a perfect mix of Dijon mustard, grated horseradish, garlic butter & Frank's hot sauce. BBQ sauce also available$10.95
Bruschetta Tomato
$8.95
Garlic Knots
$4.25
Goat Cheese Marinara
Baked herbed goat cheese with spicy marinara & Italian bread for dipping$10.95
Spicy Chorizo Meatballs
Topped with mozzarella cheese & hatch chili cream sauce, served with toasted bread$8.95
Spinach Artichoke Dip
Fresh spinach sautéed with garlic, Alfredo sauce, Parmesan & mozzarella cheese, artichokes & a hint of Wise Guy's hot sauce. Served with Italian bread$10.95
The Trio
$4.99
Tony's Fried Mac & Cheese
Cheesy mac & cheese stuffed with bacon, pepperoni and hatch New Mexico chilies. Hand battered with Italian bread crumbs and deep-fried. Served in a bed of marinara with a side of chorizo sauce$8.45
Wise Guys Meatballs
2 large meatballs topped with mozzarella cheese & marinara sauce, served with toasted bread$8.95
Wise Guys Pizza Rolls
Our homemade pizza dough filled with your choice of two pizza toppings & mozzarella. Baked golden brown then brushed with garlic butter & dusted with Parmesan cheese. Served with a side of marinara$11.45
Wise One's Fried Cheese
Breaded and fried mozzarella cheese over a bed of marinara sauce and Parmesan cheese. Served with hatch chili cream sauce for dipping$9.95
Specialty Pizza's
Half & Half Specialty Pizza
Two favorites, one pizza. Build your perfect Half & Half by choosing any two specialty pizzas, or pair a specialty with our Kitchen Sink for a simple side like pepperoni or cheese. **Photo is 1/2 Don All Meat and 1/2 My Hot Honey**
Kitchen Sink
Want everything on your pizza but the kitchen sink? It starts with Red Sauce and Mozzarella cheese, then YOU get to choose up to 6 toppings for a base price. If you need more than 6 toppings, it will be an additional charge per topping.
Angelo's Vegetable
Hand-tossed Thick Crust with Balsamic Vinaigrette as the sauce. Topped with Mozzarella, Zucchini, Yellow Squash, Eggplant, Red Onions, Red Bell Peppers, Mushrooms, Roma Tomatoes, Garlic and finished with Parmesan cheese.
Pizza Bianco
Hand-tossed Thick Crust with Alfredo Sauce. Topped with Mozzarella, Asiago, Ricotta, Garlic, Garlic Chicken, Caramelized Onions, Mushroom and topped with Parmesan.
Cement Shoes
Thin Crust with our house made Alfredo sauce. Topped with Mozzarella, Parmesan, Capers, Sautéed Shrimp and finished with Dried Oregano.
Chicago Joe
Thin Crust with our house made Red Sauce. Topped with Mozzarella, Pepperoni, Salami, Capicola, and Pepperoncinis. Cut into squares.
Don All Meat
Hand-tossed Thick Crust with our house made Red Sauce. Topped with Mozzarella, Pepperoni, Sweet Sausage, Canadian Bacon, Bacon, and Meatball.
Flamethrower
Hand-tossed Thick Crust with Spicy Marinara. Topped with Mozzarella, Pepper Jack, Spicy Sausage, Jalapeno, Onions and topped with Fresh Basil.
G.R.A.C.E.
Thin Crust with a Garlic Oil base. Topped with Roma Tomatoes, Asiago, Parmesan, Capicola and finished with Fresh Basil.
Gangsta BBQ Chicken
Hand-tossed Thick Crust with BBQ Sauce. Topped with Pepper Jack, Provolone, Roasted Garlic Chicken, Red onions and finished with fresh Cilantro.
Godfather Supreme
Hand-tossed Thick Crust with our house Red Sauce. Topped with Mozzarella, Pepperoni, Bacon, Sweet Sausage, Meatball, Black Olives, Mushrooms, Green Bell Peppers, and Onions.
Good Fella's 5 Cheese
Thin Crust topped with our House Alfredo Sauce and Garlic Oil. Topped with Mozzarella, Asiago, Parmesan, Provolone, feta cheese and topped with Dried Oregano.
Hitman
Hand-tossed Thick Crust with an Oregano Ranch Base. Topped with Provolone, Garlic Chicken, Garlic, Bacon, Roma Tomatoes and finished with fresh Parsley.
Honolulu Slim
Hand-tossed Thick Crust with our House Red Sauce. Topped with Mozzarella, Bacon, Canadian Bacon and Pineapple.
Hot Honey
Hand-tossed Thick Crust with Spicy Marinara. Topped with Mozzarella, Provolone, Salami, Pepperoni, Goat Cheese. Finished with Fresh Arugula and drizzled with Hot Honey.
Mama Mia Bruschetta
Thin Crust with a Garlic Oil base. Topped with Asiago, Parmesan, Bruschetta Tomatoes, Red Onion, Garlic and finished with Fresh Basil.
Margherita Classico
Thin Crust with a Garlic Oil base. Topped with Mozzarella, Parmesan, Roma Tomatoes and topped with fresh Basil.
Mediterranean
Thin Crust with a Balsamic Vinaigrette sauce. Topped with Artichoke Heart, Kalamata Olives, Fresh Spinach, Garlic, Sun Dried Tomatoes, and Feta Cheese.
MetroPort MacDaddy
Thin Crust with our house made Hatch Green Chili Cream Sauce. Topped with Cheddar, Garlic Chicken, Bacon, Jalapeno, Bread Crumbs, Parmesan and topped with Fresh Basil.
Milan Pizza
Hand-tossed Thick Crust with our house Red Sauce. Topped with Mozzarella, Spicy Sausage, Sweet Sausage, Mushrooms, Caramelized Onions and topped with Parmesan.
Mobster
Hand-tossed Thick Crust with Red Sauce. Topped with Mozzarella, Pepper Jack, Caramelized Onions, Spicy Sausage, Jalapeno, and Pineapple. Finished with Parmesan, Fresh Basil and drizzled Hot Honey.
Pretty Boy Pesto
Thin Crust with Pesto base. Topped with Asiago, Parmesan, Sun Dried Tomatoes, Pepitas and topped with sliced Avocado.
Rocky Graciano
Hand-tossed Thick Crust with Alfredo Sauce. Topped with Mozzarella, Garlic, Caramelized Onions, Sweet Sausage and topped with Fresh Basil.
Tommy Gun
Thin Crust with Spicy Marinara Sauce. Topped with Pepper Jack, Cheddar, Parmesan, Spicy Sausage, Bruschetta Tomatoes, Hatch Green Chilies, Garlic, Red Onions and topped with Hatch Green Chili Sauce and Fresh Cilantro.
Uncle Ray From Cali
Hand-tossed Thick Crust with both Red Sauce and Alfredo Sauce. Topped with Mozzarella, Fresh Spinach, Garlic Chicken, Garlic, Bacon, Roma Tomatoes, Feta, and topped with Sliced Avocado.
Untouchable
Hand-tossed Thick Crust with an Oregano Ranch Base. Topped with Mozzarella, Pepper Jack, Garlic Chicken, Garlic and topped with Wise Guys Buffalo Sauce and Fresh Green Onions.
Vinny
Hand-tossed Thick Crust with Alfredo Sauce. Topped with Mozzarella, Asiago, Parmesan, Gorgonzola, Sliced Sausage, Bruschetta Tomatoes and topped with Fresh Basil.
Wise Gal's BBQ
Thin Crust with a BBQ Sauce base. Topped with Garlic Chicken, Pepper Jack, Cheddar and tossed salad mixed with Romaine Lettuce, Black Beans, Roasted Corn, Hatch Green Chilies, Red Onions, Tri-Colored Tortilla Strips and Cilantro.
Build Your Own Pizza
Build Your Own - Personal
Your pizza, your rules! Start with our fresh 8" crust, choose your sauce, cheese it up, and pile on the toppings. We will make it just how you like it. **Each BYO automatically comes with House Red Sauce and freshly shredded Mozzarella Cheese.**$7.75
Build Your Own - Small
Your pizza, your rules! Start with our fresh 10" crust, choose your sauce, cheese it up, and pile on the toppings. We will make it just how you like it.$11.00
Build Your Own - Medium
Your pizza, your rules! Start with our fresh 14" crust, choose your sauce, cheese it up, and pile on the toppings. We will make it just how you like it.$16.75
Build Your Own - Large
Your pizza, your rules! Start with our fresh 16" crust, choose your sauce, cheese it up, and pile on the toppings. We will make it just how you like it.$18.75
Salads
Antipasto Salad
Asiago Caesar Salad
House croutons, shaved Asiago cheese, tossed in Asiago Caesar dressing over Romaine and topped grated Parmesan cheese
Candied Walnut Salad
Gorgonzola cheese, Dried Cranberries, glazed Walnuts, Granny Smith's Apple slices & Red Onions over Spring Mix with Balsamic Vinaigrette Dressing
Green Salad
Romaine Lettuce, Roma Tomatoes, Mozzarella cheese & Pepperoncinis with your choice of dressing.
Mediterranean Salad
Sliced Cucumbers, Kalamata Olives, Roma Tomatoes, Feta cheese, Red Onions & Sun-dried Tomatoes over Spring Mix with Basil Vinaigrette
Southwest Chicken Salad
Black Beans and Roasted Corn Mix, Hatch Green Chilies, Roma Tomatoes, Red Onions, Cilantro, Roasted Red Pepper, Garlic Chicken, Cheddar & Pepper Jack cheese. Tossed with House BBQ sauce and finished with Tri-Colored Tortilla Strips.
Wedge Salad
Wedge of Crispy iceberg lettuce, topped with Roma Tomatoes, Gorgonzola cheese, crisp bacon bits and our Gorgonzola blue cheese dressing
Wise Guys House Salad
Cucumbers, Shredded Cheddar, Dried Cranberries, Bacon, Croutons, Roma Tomatoes & Red Onions over Romaine Lettuce. Served with your choice of dressing.
Pasta
Spaghetti & Meat Sauce
Served with roasted garlic bread$11.95
Spaghetti Marinara
$9.95
Spaghetti Arrabbiata
Spicy sauce$9.95
Fettuccine Alfredo
Asiago cream sauce, Parmesan cheese$11.45
Macaroni & Cheese
$9.95
Creamy Chorizo Penne
Chorizo, spinach, hatch New Mexico chilis, red onions, cilantro with a white wine cream sauce$12.55
Creamy Alfredo Fusilli
White wine, alfredo, garlic chicken, bruschetta tomatoes, fresh basil, roasted corn, garlic & Parmesan cheese with fusilli pasta$11.95
Roasted Vegetable Fusilli
Roasted zucchini, yellow squash, eggplant, mushrooms, red bell pepper & roasted garlic, sautéed with balsamic vinaigrette, tossed with fusilli pastal$11.95
Creamy Pesto Tortellini
Tri-colored cheese tortellini with creamy pesto sauce & topped with bruschetta-style tomatoes$11.95
Vito's Lasagna
6 layers of lasagna noodles with spiced ricotta cheese, spinach, meat sauce, Parmesan cheese, garlic and oregano$12.95
Shrimp Scampi Linguine
White wine lemon roasted garlic sauce with sautéed white shrimp, capers & Parmesan cheese$13.95
Chicken Parmesan
Parmesan encrusted chicken layered with Asiago, mozzarella & marinara over angel hair pasta$12.95
Half Sandwiches
HALF Raging Bull Meatball Sub
Fresh meatballs, marinara, melted mozzarella & sprinkled with Parmesan on an amoroso roll$8.45
HALF Chorizo Meatball Sub
Fresh meatballs, marinara, melted mozzarella & sprinkled with Parmesan on an amoroso roll$8.45
HALF Chicken Parmesan Sub
Parmesan encrusted chicken layered with Asiago, mozzarella & marinara on an amoroso roll$8.45
HALF Capone's Hot Italian Sub
Capicola, pepperoni, salami, melted provolone, grated Romano, balsamic reduction, romaine, roma tomatoes & pepperoncinis with Italian dressing on an amoroso roll$8.45
HALF Lucky Luciano's Chicken Filly Sandwich
Roasted garlic chicken, sautéed peppers & onions, Wise Guys hot sauce, melted provolone on an amoroso roll$8.45
HALF California Sub
Our sliced garlic chicken, crisp bacon, avocado, roma tomato, provolone, spinach & oregano ranch on an amoroso roll$8.45
HALF Babyface Vinny's Sausage Sub
Italian sausage, sautéed peppers & onions, marinara & melted mozzarella on an amoroso roll$8.45
Full Sandwiches
FULL Raging Bull Meatball Sub
Fresh meatballs, marinara, melted mozzarella & sprinkled with Parmesan on an amoroso roll$10.45
FULL Chorizo Meatball Sub
Fresh meatballs, marinara, melted mozzarella & sprinkled with Parmesan on an amoroso roll$10.45
FULL Chicken Parmesan Sub
Parmesan encrusted chicken layered with Asiago, mozzarella & marinara on an amoroso roll$10.45
FULL Capone's Hot Italian Sub
Capicola, pepperoni, salami, melted provolone, grated Romano, balsamic reduction, romaine, roma tomatoes & pepperoncinis with Italian dressing on an amoroso roll$10.45
FULL Lucky Luciano's Chicken Filly Sandwich
Roasted garlic chicken, sautéed peppers & onions, Wise Guys hot sauce, melted provolone on an amoroso roll$10.45
FULL California Sub
Our sliced garlic chicken, crisp bacon, avocado, roma tomato, provolone, spinach & oregano ranch on an amoroso roll$10.45
FULL Babyface Vinny's Sausage Sub
Italian sausage, sautéed peppers & onions, marinara & melted mozzarella on an amoroso roll$10.45
Little Italy (Kids)
Calzones
Small Calzone
Starts with Parmesan, mozzarella, Asiago & ricotta cheese. Your choice of two toppings. Served with a side of marinara sauce. Additional toppings extra$13.95
Medium Calzone
Starts with Parmesan, mozzarella, Asiago & ricotta cheese. Your choice of two toppings. Served with a side of marinara sauce. Additional toppings extra$17.95
Large Calzones
Starts with Parmesan, mozzarella, Asiago & ricotta cheese. Your choice of two toppings. Served with a side of marinara sauce. Additional toppings extra$21.95
Desserts
Extra Sauces
Alfredo Sauce
Asiago Caesar Dressing
Balsamic Vinaigrette Dressing
Basil Vinaigrette Dressing
BBQ Wing Sauce
$0.50+
Beer Cheese
$0.50+
Buffalo Wing Sauce
$0.50+
Creamy Italian Dressing
Gorgonzola Bleu Cheese Dressing
Hatch Chilies Cream Sauce
$0.50+
Marinara Sauce
$0.50+
Meat Sauce
$0.50+
Oregano Ranch Dressing
Spicy Marinara Sauce
$0.50+
Catering
Full Antipasto Salad
Serves 15 - 20 People$69.95
Full Mediterranean Salad
Serves 15 - 20 People$64.95
Full Pan Asiago Caesar Salad
Serves 15 - 20 People$64.95
Full Pan Candied Walnut Salad
Serves 15 - 20 People$59.95
Full Pan Capones Cold Italian Sub
Serves 15 - 20 People$70.00
Full Pan Chicken Alfredo
$110.00
Full Pan Chicken Parmesan with Angel Hair pasta
Serves 15 - 20 People$115.00
Full Pan Cinnamon Knots
Serves 15 - 20 People$65.00
Full Pan Creamy Pesto Tortellini
Serves 15 - 20 People$115.00
Full Pan Garlic Knots
Served with Marinara$50.00
Full Pan Goat Cheese Marinara
Baked herbed Goat Cheese with SPICY Marinara & Italian Bread for Dipping$110.00
Full Pan Green Salad
Serves 15 - 20 People$46.95
Full Pan Penne Pasta with Choice of Sauce
Serves 15 - 20 People$100.00
Full Pan Penne Pasta with Meat Sauce
Serves 15 - 20 People$115.00
Full Pan Pepperoni Rolls
Served with Marinara$115.00
Full Pan Roasted Vegetable Fusilli
Serves 15 - 20 People$100.00
Full Pan Shrimp Scampi
Serves 15 - 20 People$115.00
Full Pan Southwestern Chicken Salad
Serves 15 - 20 People$59.95
Full Pan Spaghetti Marinara
$100.00
Full Pan Spinach & Artichoke Dip
Served with Italian Bread$110.00
Full Pan Vito's lasagna with Meat Sauce
Serves 15 - 20 People$115.00
Full Pan Wise Guys House Salad
Serves 15 - 20 People$59.95
Half Antipasto Salad
Serves 10 -12 People$39.95
Half Mediterranean Salad
Serves 10 -12 People$39.95
Half Pan Asiago Caesar Salad
Serves 10 -12 People$39.95
Half Pan Candied Walnut Salad
Serves 10 -12 People$39.95
Half Pan Capones Cold Italian Sub
Serves 10 - 12 People$45.00
Half Pan Chicken Alfredo
$60.00
Half Pan Chicken Parmesan with Angel Hair Pasta
Serves 10 -12 People$70.00
Half Pan Cinnamon Knots
Serves 10 - 12 People$35.00
Half Pan Creamy Pesto Tortellini
Serves 10 -12 People$70.00
Half Pan Garlic Knots
Served with Marinara$30.00
Half Pan Goat Cheese Marinara
Baked herbed Goat Cheese with SPICY Marinara & Italian Bread for Dipping$65.00
Half Pan Green Salad
Serves 10 -12 People$27.95
Half Pan Penne Pasta with Choice of Sauce
Serves 10 -12 People$65.00
Half Pan Penne Pasta with Meat Sauce
Serves 10 -12 People$70.00
Half Pan Pepperoni Rolls
Served with Marinara$70.00
Half Pan Roasted Vegetable Fusilli
Serves 10 -12 People$65.00
Half Pan Shrimp Scampi
Serves 10 -12 People$70.00
Half Pan Southwestern Chicken Salad
Serves 10 -12 People$34.95
Half Pan Spaghetti Marinara
$55.00
Half Pan Spinach & Artichoke Dip
Served with Italian Bread$65.00
Half Pan Vito's Lasagna with Meat Sauce
Serves 10 -12 People$70.00
Half Pan Wise Guys House Salad
Serves 10 -12 People$34.95Penne Pasta with Marinara
Penne Pasta with Alfredo
Penne Pasta with Meat Sauce
Vito's Lasagna
Green Salad
House Salad
Candied Walnut Salad
Tony's Fried Mac & Cheese
Garlic Knots
Pepperoni Pizza Rolls
Wise Guy's Wings
Full Pan Chicken Alfredo
$110.00
1
All hours
| Sunday | 10:30 am - 9:45 pm |
| Monday | 10:30 am - 8:45 pm |
| Tuesday | 10:30 am - 8:45 pm |
| Wednesday | 10:30 am - 9:45 pm |
| Thursday | 10:30 am - 9:45 pm |
| Friday | 10:30 am - 9:45 pm |
| Saturday | 10:30 am - 9:45 pm |
Restaurant info
Wise Guys Pizzeria offers handcrafted pizzas, classic pasta dishes, and a curated selection of premium draft beers, proudly serving the communities of Grapevine and Roanoke.
Location
Similar restaurants in your area
© 2026 Toast, Inc.
Made with 
in Boston
in Boston
