WiseGuys Pizza Buffalo 1965 Seneca Street Buffalo NY 14210

Hot pizza. Saucy wings. A combo that hits harder than a Sunday night kickoff 🔥🍕 Whether you’re hosting Bills parties, grad parties, or just dinner with the kids — Wiseguys Pizza & Wing Combos bring the flavor every time. Big boxes, bold Buffalo taste, zero stress.

The biggest slices you’ll find on Seneca Street. 🍕 First come, first served — so we recommend ordering ahead!

Gooey cheese, cup-n-char, sweetened sauce — just the way Buffalo pizza should be. 🍕🔥

Nothing hits like an ice-cold Coca-Cola with a hot Buffalo-style pizza 🧊🥤🍕 Whether you’re grabbing slices, feeding the family, or loading up for game day — crack open a frosty Coke and let Wiseguys handle the flavor. Because great pizza deserves an ice-cold partner.

When the basics ain’t smacking… it’s time to level up 😎🍕 A whole lineup of Buffalo-style specialty pizzas — bold flavors, real attitude, available in ALL sizes. Go ahead… surprise yourself and try something different tonight.

Mouth-watering Buffalo-style pizza since 1992 🔥🍕 Made the way the old man taught us — crispy, cheesy, no shortcuts. Personals. Larges. X-Large. Sheet Pizzas. Gluten-Free. However you want it… we’re cooking.

🔥 Cold Cut Subs stacked the Buffalo way. Ham, salami, capicola, turkey, and assorted meats piled high with crisp lettuce, tomato, and onion — finished with our house oil and spices on a fresh hoagie roll. Big bites. Bold flavor. No skimping. South Buffalo certified. 🥖🔥

🔥 A variety of HOT subs — your way. From us to your belly 🥖🔥 Add your condiments. Add your wing sauce. Add bacon. Make it messy. Make it bold. Make it YOUR way. South Buffalo flavor stacked high.

Finely chopped steak, seasoned chicken, Italian sausage, turkey & more stacked high with fresh sautéed onions — peppers and mushrooms if you’re feeling dangerous 😈🔥 Finished the Buffalo way on a toasted hoagie roll with melty cheese and straight street-corner attitude. Big. Messy. Built like a true 716 classic. Available on an 8", 12", or a seeded 18" roll… because around here we don’t do small energy 🍞💪

Buffalo’s best hot wings, BBQ, Honey Mustard, Loganberry and more — tossed the way the 716 likes it. Crispy, saucy, and finished with our homemade blue cheese because ranch ain’t the boss here. South Buffalo flavor on every bite.

🍗 Boneless Wings… SouthBuffalo style, no excuses 🔥 Right here on Seneca Street, we’re tossing ‘em crispy, saucy, and reckless — from Hot 🔥 to Honey Mustard 🍯 to Loganberry 🍒 and everything in between. Perfect for game day, dinner with the kids, or when you just don’t feel like fighting with bones 😏 #SouthBuffalo #SenecaStreet

Don’t overthink it — sometimes you just need crispy Buffalo-style chicken fingers done right 🔥🍗 Golden fried, juicy inside, and ready to be dunked in whatever sauce matches your mood. Lunch, dinner, game night… or when cooking sounds like a bad life choice.

🍗 Boneless Wings… SouthBuffalo style, no excuses 🔥 Right here on Seneca Street, we’re tossing ‘em crispy, saucy, and reckless — from Hot 🔥 to Honey Mustard 🍯 to Loganberry 🍒 and everything in between. Perfect for game day, dinner with the kids, or when you just don’t feel like fighting with bones 😏 #SouthBuffalo #SenecaStreet

Homemade salads like grandma made every summer 🥗 Chef, Antipasto, Chicken Finger, Grilled Chicken, Souvlaki, Steak & more — fresh, stacked, Buffalo bold.

Golden garlic breads, soft pretzel sticks, dessert breadsticks, classic breadsticks — hot, buttery, and straight-up irresistible 🔥🥖 Crispy edges, fluffy centers, and that Buffalo-style flavor that hits different. Perfect for dipping, sharing… or not. South Buffalo cravings start here.

Ricotta. Mozzarella. Folded, fired, and built like a straight-up Wiseguys weapon 🔥🥟 Our Calzone comes loaded with creamy ricotta and melty mozzarella — then you make it dangerous… add any toppings you want for that extra charge and extra attitude. Buffalo-style comfort with a criminal record.

Choose your weapons the Wiseguys way 🍝🔥 Pastas, Pizza Packs, Chicken Wings, Boneless, Chicken Fingers, Subs & Wraps — stack it up with ANY side, ice-cold drinks to quench the thirst, and don’t forget the desserts to finish the job. 🎉 Having a party? Grad parties, Super Bowl parties, youth sports events, business meetings — we got you covered with catering. Just give us 24-hour notice and we’ll handle the rest, South Buffalo style.

🍟 Hot. Crispy. Shake-worthy. 🍟 Our French Fries don’t just show up… they show OFF. Upgrade to Specialty Fries or get ‘em Shaken in your favorite wing sauce — sweet, spicy, buffalo, or straight savage 🔥 Perfect for Bills parties, late-night cravings, or stealing a few off your kid’s plate (we won’t tell 😏).

Crunch Wraps & Pizza Logs — Buffalo Style Trouble 🔥🌯 Our Classic Pizza Logs (4ct) come crispy and ready to be shaken in ANY homemade wing sauce — because basic ain’t our style. The Crunch Wrap lineup is straight dangerous: Steak & Cheese, Mac & Cheese, Sausage & Hot Pepper, and Buffalo Chicken… all melty, messy, and built for dipping. South Buffalo flavor with street-corner attitude — choose your sauce and get reckless.

Don’t forget the little things that make a BIG difference 🍕🔥 Need plates, napkins, forks, ketchup, blue cheese, ranch or all the extras? We got you covered — because real Wiseguys know the setup matters just as much as the food. Perfect for parties, game day, or dinner with the crew.

🍰 Sweet cravings don’t stand a chance at MaryJane’s Desserts 😍 Fried Dough… Cheesecake… Cannolis… Chocolate… Red Velvet — and honestly, who knows what she’s gonna come up with next 🔥 If you’ve got a sweet tooth, consider this your warning… once you start, there’s no turning back.

4 Mozzarella Planks — Buffalo style 🔥🧀 Crispy, melty, and built like a lake-effect snowstorm… big, bold, and no holding back. Served up golden and ready to dip like a true 716 legend.