WiseGuys Pizza Buffalo 1965 Seneca Street Buffalo NY 14210

The biggest slices you’ll find on Seneca Street. 🍕 First come, first served — so we recommend ordering ahead!

Gooey cheese, cup-n-char, sweetened sauce — just the way Buffalo pizza should be. 🍕🔥

It’s late night and we’re still slingin’ 🔥🍕 Serving Buffalo, West Seneca, Lackawanna, Cheektowaga & the First Ward . Stop searching “late night near me” — you already found it.

🌙🍕 South Buffalo late nights just hit different at Wiseguys. From Seneca Street to Downtown — ovens still hot and delivery rolling through DoorDash 🚗💨 Stop scrolling “food near me”… your pizza spot is right here 🔥

Nothing hits like an ice-cold Coca-Cola with a hot Buffalo-style pizza 🧊🥤🍕 Whether you’re grabbing slices, feeding the family, or loading up for game day — crack open a frosty Coke and let Wiseguys handle the flavor. Because great pizza deserves an ice-cold partner.

Buffalo’s best hot wings, BBQ, Honey Mustard, Loganberry and more — tossed the way the 716 likes it. Crispy, saucy, and finished with our homemade blue cheese because ranch ain’t the boss here. South Buffalo flavor on every bite.

Choose your weapons the Wiseguys way 🍝🔥 Pastas, Pizza Packs, Chicken Wings, Boneless, Chicken Fingers, Subs & Wraps — stack it up with ANY side, ice-cold drinks to quench the thirst, and don’t forget the desserts to finish the job. 🎉 Having a party? Grad parties, Super Bowl parties, youth sports events, business meetings — we got you covered with catering. Just give us 24-hour notice and we’ll handle the rest, South Buffalo style.

Don’t forget the little things that make a BIG difference 🍕🔥 Need plates, napkins, forks, ketchup, blue cheese, ranch or all the extras? We got you covered — because real Wiseguys know the setup matters just as much as the food. Perfect for parties, game day, or dinner with the crew.

🍰 Sweet cravings don’t stand a chance at MaryJane’s Desserts 😍 Fried Dough… Cheesecake… Cannolis… Chocolate… Red Velvet — and honestly, who knows what she’s gonna come up with next 🔥 If you’ve got a sweet tooth, consider this your warning… once you start, there’s no turning back.